Inflammasome assembly and gasdermin D biology in health and disease

题目:Inflammasome assembly and gasdermin D biology in health and disease

演讲人:Hao Wu, Ph.D. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Member of National Academy of Sciences

时间:2019年3月14日,10:00-11:30

地点:金光生命科学大楼邓祐才报告厅

主持人:肖俊宇研究员


摘要:

My laboratory has been interested in using structural biology to address fundamental questions in immunological processes. In innate immunity, the important family of complexes, known as inflammasomes, activate inflammatory caspases to induce cytokine processing and pyroptotic cell death. In this presentation, I will focus on 1) assembly of inflammasomes 2) cellular localization of inflammasomes and 3) gasdermin D structure, function and inhibitor discovery.

欢迎各位老师同学积极参加!