龚骞 研究员
植物抗病毒免疫研究组
北京大学 现代农学院 研究员，博士生导师
电话：
E-mail：gongqian@pku.edu.cn
1. 植物气传性免疫与病虫害绿色防控
2. 植物广谱抗病毒免疫机制
3. 病毒传播和致病机制
植物病毒是严重威胁全球农业安全的病原物，其中约80%植物病毒依赖昆虫媒介传播。我们围绕病毒侵染循环开展研究，系统解析病毒入侵、增殖与传播过程中植物的抗病虫免疫机制及病毒的应对策略。主要研究进展包括：鉴定了挥发性化合物水杨酸甲酯的植物受体，阐明了植物气传性免疫抗病虫的分子机制和病毒的反防御策略（Nature, 2023）；解析远红光调控植物免疫的信号通路，揭示病毒干扰远红光受体核转运来逃逸宿主防御的新机制（Science Advances，2025）；首次建立钙信号与RNAi通路之间的联系，阐明植物感知病毒入侵启动抗病毒RNAi 通路核心基因表达的早期信号及调控机制，同时也揭示了病毒的反防御机制（Cell Host & Microbe，2021）。
Gong Q, He L, Huang F, Wang Y, Xie J, Hong Y, Liu Y. (2025) Far-red light orchestrates antiviral defense in plants. Sci. Adv., 11: eadz7663.
Liu J, Gong Q. (2025) Rewiring nlrs for broad and cross-species plant immunity. Mod. Agric., 3: e70031.
Wang Y, Gong Q, Liu Y. (2025) Multifaceted roles of autophagy in plant–virus–insect interactions. New Phytol., 248: 1166-1170.
Gong Q, Wang Y, Zhang X, Zhao J, Liu Y, Hong Y. (2024) Plant airborne defense against insects, viruses, and beyond. Trends Plant Sci., 29: 283-285.
Wang Y, Gong Q, Liu Y. (2024) Interplant communication: An emerging battlefield in plant-aphid-virus interactions. Sci. China Life Sci., 67: 1069-1071.
Gong Q, Wang Y, He L, Huang F, Zhang D, Wang Y, Wei X, Han M, Deng H, Luo L, Cui F, Hong Y, Liu Y. (2023) Molecular basis of methyl salicylate-mediated plant airborne defence. Nature, 622: 139-148.
Wang Y, Gong Q, Jin Z, Liu Y, Hong Y. (2022) Linking calcium and RNAi signaling in plants. Trends Plant Sci., 27: 328-330.
Gong Q, Wang Y, Jin Z, Hong Y, Liu Y. (2022) Transcriptional and post-transcriptional regulation of RNAi-related gene expression during plant-virus interactions. Stress Biol., 2(1): 33.
Wang Y, Gong Q, Huang F, He L, Liu Y. (2022) Live imaging and quantitation of insect feeding-induced Ca2+signal using GCaMP3-based system in Nicotiana benthamiana.STAR Protoc., 3: 101040.
Wang Y, Gong Q, Wu Y, Huang F, Ismayil A, Zhang D, Li H, Gu H, Ludman M, Fatyol K, Qi Y, Yoshioka K, Hanley-Bowdoin L, Hong Y, Liu Y. (2021) A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants. Cell Host Microbe, 29: 1393-1406.
刘俭俭、谢印帅、苏琳珂
